Sarah Thomas

Dr Sarah Thomas is a reader in physiology. Her research projects focus on characterising the delivery of small molecule and biologic therapies across the blood-brain and blood-cerebrospinal fluid barriers in health and disease. An area of particular interest is membrane transporters and the relationship between drug concentrations in the CSF and the brain tissue. In order to understand molecule transport across these barriers she has developed and deployed a variety of experimental models. These range from in silico simulations through to cell culture and whole animal studies. She has also shared skills and expertise through several collaborations (e.g. Amgen, GSK, Ossianix, Institute of Psychiatry, University of Glasgow, London School of Hygiene and Tropical Medicine and Walter Reed Army Institute of Research, USA).